The Heart Foundation supports a large and diverse research program devoted to unraveling the causes of heart disease at a genetic and molecular level, improving methods of early detection, and developing and testing new preventive and therapeutic strategies.
Following is a sample of some of the hundreds of articles published by P.K. Shah, M.D. on his revolutionary heart disease research. Much of this work was made possible, in part, by funding from The Heart Foundation:
Current Atherosclerosis Reports (Vol. 9, 2007)
Immunization for Atherosclerosis
Circulation Research (Vol. 100, 2007)
Innate Immune Pathway Links Obesity to Insulin Resistance
Current Pharmaceutical Design (Vol. 13, No. 00, 2007)
Apolipoprotein A-I/HDL Infustion Therapy for Plaque Stabilization-Regression: A Novel Therapeutic Approach
European Heart Journal (11/22/06)
Inhibition of CETP as a novel therapeutic strategy for reducing the risk of atherosclerotic disease
Journal of the American College of Cardiology (Vol. 48, No. 7, 2006)
Bone Marrow Transplantation Shows Superior Atheroprotective Effects of Gene Therapy With Apolipoprotein A-I Milano Compared With Wild-Type Apolipoprotein A-I in Hyperlipidemic Mice
Nature Clinical Practice: Cardiovascular Medicine (Vol. 2, No. 12, December 2005)
Immunomodulation of atherosclerosis with a vaccine
Biochemical and Biophysical Research Communications (338, 2005)
Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (-/-) mice
Circulation (2004)
Recombinant Human Antibodies Against Aldehyde-Modified Apolipoprotein B-100 Peptide Sequences Inhibit Atheroslcerosis
Journal of the American College of Cardiology (Vol. 44, No. 6, 2004)
Rapid Reversal of Endothelial Dysfunction in Hypercholesterolemic Apolipoprotein E-Null Mice by Recombinant Apolipoprotein A-I Milano-Phospholipid Complex
Circulation (2003)
Intramural Delivery of Recombinant Apolipoprotein A-I Milano/Phospholipid Complex (ETC-216) Inhibits In-Stent Stenosis in Porcine Coronary Arteries
Enter your email address here to subscribe to our mailing list for announcements.
